|
KMID : 0387720150260010075
|
|
Korean Journal of Blood Transfusion
2015 Volume.26 No. 1 p.75 ~ p.80
|
|
|
Therapeutic Plasma Exchange for a Patient with Severe Cold Agglutinin Disease
|
|
양내리:Yang Na-ery
박설희:Park Shol-Hui/정혜선:Chung Hae-Sun/문영철:Moon Young-Chul/유신애:Yu Shin-Ae/권민정:Kwon Min-Jung/우희연:Woo Hee-Yeon/오석중:Oh Suk-Joong/이미애:Lee Mi-Ae
|
|
|
Abstract
|
|
|
|
Cold agglutinin disease is a kind of autoimmune hemolytic anemia, caused by cold agglutinin, serum autoantibodies activated at reduced body temperatures to produce red blood cell agglutination and hemolysis. In this paper we described a case of severe hemolytic anemia in a cold agglutinin disease patient treated with therapeutic plasma exchange. Therapeutic plasma exchanges were performed four times every other day. Over the same period, a total of 8 units of washed red blood cells were transfused. Then hemoglobin was increased from 4.0 g/dL to 7.8 g/dL. On the 12th hospital day hemoglobin level was decreased again to 4.2 g/dL and fludarabine chemotherapy was started on the 14th hospital day. The patient’s symptoms were relieved and she was discharged on the 30th hospital day. As in this case, therapeutic plasma exchange could be considered as secondary therapy for temporary improvement of acute severe hemolytic anemia in cold agglutinin disease.
|
|
|
KEYWORD
|
|
|
Therapeutic plasma exchange, Cold agglutinin disease, Autoimmune hemolytic anemia
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|